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The phrase "a distinct question" is correct and usable in written English.
You can use it when referring to a question that is clear and separate from others, often in discussions or analyses.
Example: "In this debate, we must address a distinct question regarding the impact of climate change on agriculture."
Alternatives: "a separate question" or "a specific question".
Exact(4)
A distinct question: Is "obtain" not simply a fancy way of saying "exists"?
The influence of Matrigel on established tumors, however, is a distinct question from its impact on normal cells.
The factors that govern VEGFR3 expression in arterial endothelial cells therefore appear to be complex and represent a distinct question separate from the one we address in this manuscript.
The most that a low E-value for sequence similarity (say, from a BLAST search) can do is show that the observed degree of sequence similarity is greater than that expected by random chance — the assessment of homology, on the other hand, is a distinct question.
Similar(56)
In "On the Facts Underlying Geometry," Helmholtz investigates a related, but distinct question.
The extent of our military commitment is a separate and distinct question but it is disingenuous to appear almost baffled about why we are there at all.
A related but distinct question is the evolution of the labeling itself [ 12].
A related but distinct question concerns the set of species which should be included in the mixture model.
A related but distinct question is how to bolster the demand for drugs in low-income countries (and hence firms' willingness to engage in R&D); we touch on this in a section below in which we discuss Advance Purchase Commitments and other financial innovations.
In terms of its legacy, London 2012 throws up a few distinct questions: did it bring in more money than it cost?
Finally, we note that the issue of recognizing same-sex unions from other jurisdictions presents a distinct legal question.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com