The phrase "a distinct conformation of" is correct and usable in written English.
It can be used when describing a specific shape or arrangement of something, often in scientific or technical contexts.
Example: "The researchers discovered a distinct conformation of the protein that enhanced its functionality."
Alternatives: "a unique structure of" or "a specific arrangement of".
Mutational and computational analysis of A1-AR revealed a distinct conformation of the second extracellular loop and a wider extracellular cavity with a secondary binding pocket that can accommodate orthosteric and allosteric ligands.
The Arg975Trp mutation introduces a large hydrophobic patch in H1' α-helix, whereas loss of Leu-954 provokes a distinct conformation of the extended coil.
Importantly, loss of Leu-954 results in a distinct conformation of the extended coil that precedes α-helix H1' (Figure 2B) and this directs unique intramolecular interactions (Supplementary Figure S7).
Ligands of CCR5, in contrast to a ligand of CXCR4, induced a clear increase in FRET efficiency, indicating that selective ligands promote and stabilize a distinct conformation of the heterodimers.
This seems to reflect the presence in "CH1641-like" scrapie of mixed conformers with different abilities to propagate in the spleen and brain or a distinct conformation of PrPd between spleen and brain in these particular isolates.
Turning the switch "on," the enzyme environment becomes the driving force to impose a distinct conformation of the 5′-deoxyadenosyl radical to avoid deleterious radical transfer.
One striking active site difference is a loop that adopts a distinct conformation as a result of an Asp → Asn change with respect to DHQS and alters the identity and orientation of a key Arg residue.
These findings argue for a substantially distinct conformation of the Gαo GoLoco1 complexes depending on the nucleotide state of the G protein.
Dr. Weiss' group is attempting to bind MYC indirectly by using PI3K-pathway blockade or aurora kinase inhibitors, which can induce a novel and distinct conformation of aurora kinase A that is unable to stabilize MYCN.
Despite the distinct conformation of RF2, its conserved catalytic GGQ motif is precisely positioned next to the CCA-end of the P-site tRNA.
Therefore, Ca2+ may also help to maintain the distinct conformation of G7, which would be crucial for binding to hFc1.
