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The phrase "a disruption in" is correct and usable in written English.
It can be used to describe an interruption or disturbance in a process, system, or situation.
Example: "The recent storm caused a significant disruption in the supply chain, leading to delays in product delivery."
Alternatives: "an interruption to" or "a disturbance in".
Exact(59)
And he never caused a disruption in the locker room.
Unsupervised reunions inevitably follow, sometimes leading to a disruption in the adoptive placement.
Awkwardness is the feeling of discomfort or anxiety that accompanies a disruption in social norms.
"It has been such a disruption in our lives," she said.
Tuesday's 18-hole finish will not cause much of a disruption in Stricker's schedule.
A shock in the condo market could come from a disruption in the economy.
What I stand for is such a disruption in the Washington establishment".
That led to a disruption in the water supply in some parts of Pakistan.
There has, however, been a disruption in Dewey's summer associate program.
Officials also are starting to address the consequences likely to flow from a disruption in payments.
"It's a red flag that causes a disruption in the clubhouse," Down said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com