Exact(1)
From a discovery point of view, compounds should not only be optimized for target binding potency but also for low unbound CL to maximize tissue equilibrating unbound drug concentrations.
Similar(59)
A related objective is to come up with recommendations about experimental design and model building techniques in situations of feedback systems from a drug discovery point of view.
From a gene discovery point of view the high degree of genetic variation in potato can be considered an advantage as not only gene expression variation but also difference in hybridization efficiency can lead to the discovery of novel associated candidate genes.
For example, a recent discovery points to a gene variant associated with a significantly increased risk of febrile seizure following vaccination for measles, mumps and rubella (the MMR vaccine) [ 90].
A recent discovery pointed to a negative correlation with technology, finding the constant presence of screens and devices in our lives to be robbing our weary brains of restful daydream moments, resulting in a tragic drop in imaginary celebrity sex for all of us.
We spent two days roaming the area: a damp dawn at Discovery Point, windy dusk at Watchman Overlook and a great hour at Rogue River Gorge, outside the park boundary.
It doesn't get as much attention as Discovery Point (which has a big parking lot), but the overlook gives you a commanding angle, looking almost straight down at Wizard Island.
Search (largely Google) has long been the access and discovery point for web services.
1.3 miles northwest: Do go to Discovery Point and imagine what it was like in 1853 to stumble on the scene.
From Discovery Point at Crater Lake National Park, the still waters surrounding Wizard Island reflect the faint colors of the sunrise painted on the clouds above.
(48) Acetoxymethylation of IPA/NO unveiled some properties that were especially intriguing from the drug discovery point of view.
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