The phrase "a disastrous combination" is correct and usable in written English.
You can use it to describe a pairing or mix of elements that leads to negative or harmful outcomes.
Example: "The lack of communication and poor planning created a disastrous combination that ultimately led to the project's failure."
Alternatives: "a terrible mix" or "a catastrophic pairing."
He and Burnett proved a disastrous combination, going 20-25.
Rising interest rates and a slowing housing market can be a disastrous combination for overstretched homeowners.
She grew up in Detroit with a father absorbed by radical Communism and a mother who she describes as "a disastrous combination of fury and depression".
Mr. Kotis said he believed there was a large audience for the show, people who not only respond to the satire but also to the underlying message that greedy corporations and selfish citizenry can be a disastrous combination.
Labour peer Lord Mandelson, the former business secretary, said: "In my lifetime, there has been no greater threat to this country than a disastrous combination of leaving the EU and a Boris Johnson premiership".
"The lesson we all drew from Bosnia," says Mats Berdal, an analyst at the International Institute of Strategic Studies in London, "is that Europeans being on the ground and Americans not is a disastrous combination".
But Big Star's fate was a perfectly disastrous combination of talent, musical ambition, personal temperament and bad luck.
The disastrous combination of a paralyzing drought, skyrocketing food prices and conflict has left over 11 million people battling hunger to survive.
Mr. Zetsche also eschewed comparison with Daimler's disastrous combination with Chrysler, a nine-year dalliance from which the German company finally extracted itself at great cost in 2007.
That would seem to be the perfect combination, or it could be the perfectly disastrous combination.
Gold-leaf accents couldn't ameliorate the mushy texture of the bluefin-tuna tartare, or redeem the disastrous combination of salmon and foie gras in the temari roll.
