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'a disadvantageous impact' is correct and usable in written English.
It can be used to describe a negative influence or consequence, especially with respect to an action, event, decision, situation, occurrence, etc. For example: "The government's decision to cut funding had a disadvantageous impact on the local community."
Exact(1)
Free radicals in smoke produce an oxidative milieu, which may promote the formation of disulfide groups in the active site of the enzyme and may also have a disadvantageous impact on PAD.
Similar(59)
In contrast, the thought behind the idea of indirect discrimination is that, if an act has a disproportionately disadvantageous impact on persons belonging to certain types of salient social groups, then the act is morally wrong and legally prohibited if it cannot meet some suitable standard of justification.
Despite the differences, these criteria have a common thought behind them: a disproportionately disadvantageous impact on the members of certain salient social groups must not be written off as morally or legally irrelevant or dismissed as mere accident, but rather stands in need of justification.
Postoperative AKI is a relatively rare complication of CABG but has a profoundly disadvantageous impact on short-term (< 30 day) prognosis.
3. Identifying the polarity of the impact to detect advantageous and disadvantageous impacts.
He moves in a disadvantageous direction.
"Yet there's still a disadvantageous industrial mix".
The fallout from a disadvantageous negotiation can reverberate for years to come.
The presence of manganese was found to have a disadvantageous influence on the combustion of chlororganics.
A further issue regarding the FT model is the maintaining of countries of the south in a disadvantageous economic specialisation.
(M ost frequently today the average prospective tenant vis-a-vis the prospective landlord occupies a disadvantageous position.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com