An E. coli motility expression data set ([ 41] series accession number: GPL2101) was obtained in a direct pair-wise comparison between a knock-out mutant of the flhDC, a master regulator of the motility/chemotaxis regulon [ 25], and its isogenic wild type strain.
This allows a direct comparison between pairs of carbons with similar micropore systems, with and without mesopores, in order to assess the role of mesoporosity in the electrochemical properties.
Network analysis of highly expressed genes typically relies on preexisting knowledge of a direct interaction between pairs of highly expressed genes.
Considering that this double mutant still contains the miR-122 complementary sequence in the 3′-UTR, the latter result confirms that direct base pairing between miRNA and the two miRNA target sites in the 5′-UTR of the HCV reporter RNA is involved in the stimulation of HCV translation.
Chopping up all communications into data packets of fixed size, and allowing machines to relay packets to each other, meant that there was no need for a direct link between every pair of machines on the network.
Thus, we assume that a direct interaction between a pair of individual proteins b and x survives the purification process with probability p ^ (b, x ), and breaks with probability 1 − p ^ (b, x ).
Our experimental design involved direct pair-wise comparison between mutant and wild type at young age (3 months, 5 individuals per group) including a dye swap comparison (a total of 10 slides).
For the sake of the analysis presented here, we will focus on direct pair-wise comparisons between samples using spotted DNA arrays conducted as dual-labeled co-hybridization assays.
To further support this statistical analysis, it was also tested if there is a significant difference between the direct pairs of A1 and B1, and A2 and B2, which would indicate the influence of gold NP alone.
The observed eclipsed geometry of dCTP and its C6−O5′ internal interaction could provide a direct link between correct W−C base pairing geometry and catalysis through transition-state stabilization as suggested above, because the C6−O5′ interaction is likely to be absent in non-W−C base paired incoming dNTPs.
