Sentence examples for a direct modification of from inspiring English sources

This is possible by a direct modification of the subchannels' frequency-domain shapes, as shown in Figure 9.

Using a direct modification of the results in [55], it follows that the deterministic Amari model (16) has solutions U ( x, t ) in the Hölder space BC α ( B ) × BC α ( [ 0, T ] ) for α ∈ ( 0, 1 ] and B ⊂ R d is the usual domain we use for the Amari model. Now consider the analogous naive guess to (36) given by V [ U ] : = ∫ B [ α 2 U ( x ) 2 − ∫ B ∫ 0 U ( y ) f ( r ) w ( x, y ) d r d y ] d x. (37).

Understanding the endocytic itinerary of PrPC is fundamental, since data in the literature indicate that both general inhibition of endocytosis [8], [12] and/or a direct modification of the internalization route of PrPC, by replacing the GPI anchor with a transmembrane sequence containing a coated pits localization motif [9], affect both the infection and the conversion processes [3], [44].

Finally, a direct modification of this arginine at position 813 (e.g. by methylation ) may occur.

The only known mechanism for a direct modification of DNA sequences after their synthesis is the methylation of nucleotides.

However, this left-shift potential was not directly related to mechanical parameters, but rather based on a direct modification of electrophysiological properties.

A major advantage of this conjugation approach is that it prevents any direct modification of the aptamer sequence involved in the binding process, since conjugation to gold nanoparticles is facilitated via the oligonucleotide extension.

The process of Pavlovian conditioning thus often enables animals to behave appropriately in anticipation of events of biological significance, without involving any direct modification of that behaviour by its success or failure.

However, we do not exclude the possibility that Plk1 directly regulates Aurora A. In such a scenario, direct modification of Aurora A by Plk1, could make Aurora A susceptible for degradation by the APC/C.

Caspase involvement in cell death is suggested also by the higher IC50 for MCF-7 cells (Table 2)—cells that are known to be caspase-3-deficient.[ 31] In this report we describe the synthesis of the new glycyrrhetinic acid derivative methyl 2-cyano-3,12-dioxo-18βH-olean-9(11),1(2 -dien-30-oate (12 -dien-30-oate the direct modification of the A and C rings of glycyrrhetinic acid.

The available evidence suggests that use of a treatment algorithm with direct modification of therapy by the physician extenders is more effective than having the extender recommend changes to the primary care provider, likely overcoming the clinical inertia often experienced by clinicians (18).