Sentence examples for a direct causative effect from inspiring English sources
Assuming the genetic associations we identified are real, they may either be due to a direct causative effect of the SNPs tested, or because these tSNPs are in linkage disequilibrium and serve as markers for the real determinant of a disease.
However, a direct causative effect of cellular senescence on ageing has never been shown.
They received blood pressure stabilization therapy with an alpha 1 adrenergic pressor agent; however, it is difficult to establish if this had a direct causative effect.
However, as pointed out by Willet et al, these in vitro studies have yet to show a direct causative effect between AGEs and the progression of osteoarthritis.
We have previously reported a direct causative effect between high PHLDA2 and late onset growth restriction in an animal model, which we attributed to placental insufficiency [23,24].
It is possible that tumour IFP may be more a marker of treatment response than have a direct causative effect on metastatic spread.
Although overexpression of these genes may not have direct causative effects on the proliferative nature of cancerous cells, these studies suggest a correlation between increased expression of mitotic genes and cancer formation.
Although some toxicologic evidence supports the potential for NO2 as a direct causative agent for respiratory health effects at high concentrations (Kelly and Sandstrom 2004), the more likely interpretation is that NO2 was a proxy for other components of the local air pollution mixture with high toxic potential.
It also highlights the fact that side-effect entries in AERS are not necessarily indicative of a direct causative relationship, and apparent statistical relations between taking drugs and side effects can appear due to other correlates, and could even appear when the drugs is prescribed to treat the side-effect.
Despite great progress, a direct causative pathway from the HD gene mutation to neuronal dysfunction and death has not yet been established.
We investigated if such anti-TG2 antibodies have a direct causative role in ataxia by injecting the anti-TG2 (class1), the anti-TG2-3-6 (control or the control (bac1) scFv into the lateral ventricle of mice and tested their effect on balance using the rotarod test [15].
