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Paris is spending an estimated half a million dollars on this project, a direct alignment to the values of its residents.
A better solution, wherever possible, is to follow a direct alignment keeping an average gradient.
Since the ancestor sequence is never known for a direct alignment, we may sample it a posteriori given the reference species nucleotide.
During the merging, the common read guides a direct alignment of different contigs, which takes linear time in the total number of reads involved in the star.
A direct alignment of this to a parallel, annotated map of the genome can provide a visually striking and intuitive way to assess the data.
Newbler assembly notation codes putative SNPs with flanking insertion characters (presumably to reflect uncertainty in indel errors), whereas most reference-guided assemblies provide a direct alignment at polymorphic positions that are easily recognized by SNP-finding packages.
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By 1960, PA 83 was realigned to a more direct alignment between Bernville and Schubert, passing through Strausstown.
A jog in the routing near Almena was removed in 1937 when Wisconsin rerouted the highway to a more direct alignment in the area.
The only change made at this time was the straightening out of the Victor Pittsford segment, which now bypassed Mendon in favor of a more direct alignment between the two villages via Bushnell's Basin.
North of Dundee, a more direct alignment to Azalia was added to US 23, turning the former routing back to local control in late 1947 or early 1948; at the same time, the last gravel section of the highway was paved near Hammond Bay in northwestern Presque Isle County.
Here, we introduce a new method, D iamund (direct alignment for mutation discovery), which takes a different approach to exome and whole-genome analysis, and as a result produces dramatically smaller sets of candidate mutations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com