Cells isolated from Crouzon mice also exhibited less alkaline phosphatase enzyme activity at day 18 of differentiation and mineralized to a diminished extent than cells isolated from wild type littermates and 2(g)).
Specifically, when both IL-6 and TGF-β1 were added together, ERK1/2 activation was observed with similar timing as with IL-6 alone but to a diminished extent.
The diminished extent of matrix mineralization after ZOL treatment was, therefore, ascribable to decreased cell proliferation and increased apoptosis, not to decreased osteogenic differentiation of osteoblasts.
Overall, the recovery process was less efficient in the cirrhotic organ, and culminated in a diminished rate and extent of the regenerative response.
As shown in Figure 1, over-expression of AtTCTP clearly suppressed the pro-apoptotic effect of BAX indicated by reduced ion leakage levels, a reduced extent of chlorosis, and a diminished amount of dead cells.
One has a diminished expectation of privacy in automobiles.
"It's a diminished version of Project Concern," said Ms. Carroll.
Mr Cameron scraped through with a diminished majority of 24.
Rats in the SR and CIH-SR groups showed a diminished concentration of triglycerides and VLDL.
But this show is not the work of a man with a diminished sense of humour.
Both CaS oxidation and reductive decomposition of CaSO4 may lead to a diminished degree of desulphurization in real combustors.
