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We then test the two solvers with a digital mouse model downloaded from the DIGIMOUSE website [ 25].
This is achieved though non-rigid registration of a digital mouse model with the animal PET image set followed by automated calculation of tracer concentrations in 22 predefined VOI representing the major organs and remaining whole body.
Do not pick it up and drop it, especially if you have a digital mouse, as this can move the sensor out of place.
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Tracer uptake was quantified by region of interest analysis using PMOD software and a 3-D digital mouse brain atlas.
A digital female mouse atlas was overlaid onto the 3D diffuse tomography reconstruction to obtain anatomical reference points.
From the segmented digital mouse CT image, we create a 3D tetrahedral mesh using an image-based mesh generator, iso2mesh [ 15], and utilities based on the CGAL library [ 14].
We used 4-dimension (4D) digital mouse whole body (MOBY) phantom and to clarify the feasibility of TV noise reduction technique in m-CT images, we compared the image performance using contrast-to-noise ratio (CNR) and coefficient of variation (COV).
This digital mouse model contains all the major organs represented in 306,773 tetrahedra.
The simulated mouse sample was generated using the Moby digital mouse model [ 6], which creates two 3-D voxelized phantoms, one containing the activity map and the second the attenuation map (μ-map) at 511 keV.
Future improvements in imaging should enable us to generate large libraries of digital mouse embryos from fertilisation to implantation that can be interrogated for quantitative information and population behaviour.
Tumour measurements were taken twice a week with a digital caliper and mice were weighed once a week.
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