Sentence examples for a difficulty in ascertaining from inspiring English sources

However, oxaliplatin functions in a non-targeted manner, posing a difficulty in ascertaining precise efficacy mechanisms.

A particular difficulty in ascertaining toxicodynamic variation experimentally is that it would ideally require precise measures of the dose delivered at the target site and this is more readily achieved in vitro, ex vivo or by pharmacologically based pharmacokinetic (PBPK) modelling.

But having a terrestrial, and not a celestial origin, we find no difficulty in ascertaining its meaning in all the parts which we allege to relate to slavery".

This is likely due to the difficulty in ascertaining a suitable set of initial values to ensure proper convergence to find the best possible GLD fit, an area where SR can provide valuable guidance and input.

An additional, practical consideration against interpreting the Reciprocity Principle to apply depending on the participant's intention is the difficulty in ascertaining a participant's intention and so in concluding whether there are reciprocal obligations.

These are areas which require a judgment by the reviewer and therefore have a subjective component or may be obscured by CPR artifact or difficulty in ascertaining whether a pulse or blood pressure was present due to lack of documentation.

Observers had difficulty in ascertaining ictal evolution, a critical feature of recognition when the seizure was short.

Indeed, such a wide range of inappropriate ED attendances underlines the difficulty in ascertaining their true rate.

The first of these studies was a retrospective case-control study, a study design that is subject to several important biases including difficulty in ascertaining the temporality of relationships, and the second has been criticised for failing to adjust for important confounders[ 3].

Ivory harvested prior to 1990, however, is still legal to sell, and the difficulty in ascertaining when ivory was taken allows for illegally harvested ivory to be passed off as "pre-ban".

Far the preponderant number of individuals belongs to the Finches & Gross-beaks There appears to be much difficulty in ascertaininGross-beaks There