It is a difficult undertaking to bring a group of travelers with various levels of outdoor skills safely into the Alaskan backcountry for an extended period of time.
This is a difficult undertaking given the limitations of the available datasets.
Though it is widely acknowledged that a stronger evidence base is necessary to support palliative care as a complex intervention, assessing research at the end-of-life can be a difficult undertaking due to the number and depth of outcomes measured [ 12].
Although the design of a platform that would meet the needs of all microfluidic experiments is a difficult undertaking, this paper provides a description of a flexure-based platform that may address generic requirements such as low cost, ease of manufacture, and repeatable alignment/sealing performance.
However, experimental determination of protein structures is often laborious, expensive and a difficult undertaking, such that only about 10% of the 4000 protein sequences that constitute the Mycobacterium tuberculosis (Mtb) proteome (1, 2) have been structurally determined (3).
I learned that to live free from the shackles of conformity is a difficult undertaking, but when we find a way to do so, in spite of imposed assumptions, we exist in a state of joyous resistance.
Rather it is an illustration of what a difficult undertaking it is, and why The Economist has always advocated looking at them all, including our own, with a critical eye.
Although this was a serious attempt to reconstruct the bridge as close to the original as possible, the Spanish scholar Durán points out that slight changes to the main body can never be avoided in the course of such a difficult undertaking.
He concludes that "without some form of forgetting, forgiving becomes a difficult undertaking".
For her part, Ms. Feliz says that taking care of three grandchildren is not a difficult undertaking.
Its time is overdue -- but if the experience of Columbia University is any indication, it will be a difficult undertaking.
