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This is a difficult issue to resolve, as a number of authors have interpreted this facilitation effect as an incomplete inhibition of muscular activity [28].
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"This is a very difficult issue to resolve in one shot," said Andrew Yang, secretary general of the Chinese Center for Advanced Policy Studies, a research organization in Taipei.
This is a more difficult issue to resolve.
"How to protect the consciences of both sides here -- pro-life tax payers and the women who want access to legal abortion -- is a most difficult issue to resolve".
Members of both parties warned that while the door had opened to some possible resolution of what has proven to be an extremely difficult issue to resolve, the outcome remains uncertain.
Whether candidate senolytics actually alleviate phenotypes though removing senescent cells or through possible off-target effects on nonsenescent cells is an important and difficult issue to resolve.
It is believed that dealing with the legacy and aftermath of Northern Ireland's Troubles will be the most difficult issue to resolve.
Iraq has a lot of difficult issues to resolve.
Timing of scheduled ultrasound laboratory sessions and the variable rate at which students acquire scanning skills can be difficult issues to resolve in a busy medical student curriculum.
Compensation for those displaced remains one of the most difficult issues to resolve.
Negotiators said that the refundability matter and the size of the top rate were the most difficult issues to resolve.
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