Sentence examples for a difficult issue is from inspiring English sources

A difficult issue is the optimal timing of pheochromocytoma excision.

A difficult issue is how to decide cut-off points which distinguish meaningfully between clearly satisfying and unsatisfactory parenting.

Finally, the selection of underlying cause of death when alcohol may be involved is a difficult issue, being potentially biased by cultural factors as well as having an arbitrary aspect due to the frequent presence of multiple alcohol-induced pathologies.

A more difficult issue is how far, if at all, a child witness should be confronted with a specific accusation of having told a lie, where the essence of the defence case is that the child's evidence is untrue.

A more difficult issue is the increase in fractures, being a more common occurrence and one that may be difficult to predict.

A more difficult issue is as to the tugs.

Using humor as a tool to confront and learn from difficult issues is a hallmark of Mr. Feiffer's work.

Sen. Mark Leno (D-San Francisco), who has a reputation for tackling particularly difficult issues, is unfazed by the challenges of the new legislative year.

How to reform the network is a difficult issue which is not discussed in this paper.  .

"The tax is going to be a difficult issue; there's no question about that," Manfred said, adding: "Like every other issue, I don't think either side has shown all its cards on that topic.

"If there's going to be a difficult issue, that's it," said Richard Block, acting director at the Michigan State University School of Labor and Industrial Relations.