Sentence examples for a difficult clinical challenge from inspiring English sources

These leaks, once managed acutely, can become chronic and represent a difficult clinical challenge.

Left-sided breast cancer patients pose a difficult clinical challenge when significant heart and contralateral breast irradiation are present, particularly with tangential uniform beams.

The treatment of metastatic disease has been and remains a difficult clinical challenge.

Patients who present with locally advanced rectal cancer (LARC) with metastatic disease present a difficult clinical challenge.

Thus, even in the ideal circumstances of a rigorous clinical trial, consistent adherence to lifestyle modification remains a difficult clinical challenge.

This may have important implications in patients with low Ccw, such as patients with IAH [ 8], obese patients or ARDS patients, where adjusting appropriate lung protective ventilation settings can be a difficult clinical challenge [ 24] and these strategies may often result in excessive hypercapnia and respiratory acidosis.

The complete regeneration of the periodontal tissues following periodontal disease remains an unmet challenge, and has presented clinicians with a remarkably difficult clinical challenge to solve given the extensive research in this area and our current understanding of the biology of the periodontal tissues.

Background: Glaucoma in children presents difficult clinical challenges.

Disentangling depression from dementia remains one of the most difficult clinical challenges for psychiatrists caring for older adults.

The isthmus is one of the more difficult clinical challenges because the area is complex and not easy to clean thoroughly by mechanical preparation.

See related Research article: The assessment of intravascular volume and the adequacy of volume resuscitation are among the most difficult clinical challenges.