The new study arrives at a slightly lower annual figure of 19,000, a difference the lead author of the COMEAP study, Fintan Hurley, attributes to differing methodology.
This discrepancy in results could be due to differing methodology: both Hill and Kotanen and Dawson et al measured leaf damage by insects, but Hokkanen and Pimental and Ricciardi and Ward examined plant survival [11], [12], [13], [34].
The similarity of results from the three different methods, while limited to the specific tasks studied, do suggest that comparing results from multiple studies may be fruitful in spite of the use of differing methodology.
This may be due to the differing methodology used in measuring HER2 status [ 6].
The conflicting data on natural history and clinical significance may be attributable to the differing methodology in many of these studies.
Of seven studies reporting any abnormal signs, two found these in 61-95% [ 5, 35] and two in 46% and 57% [ 6, 33], despite widely differing methodology and definitions.
Given the differing methodologies and therefore differing biases due to potential inclusion of false positive cases or selection of more severe cases, other reported associations are very difficult to interpret.
Considering the differing methodologies used in different studies, it is difficult to interpret the reported Kappa values with confidence.
That's why it's critical to seek information from various sources to provide you with the full picture, as differing methodologies and an ever-shifting industry force prospective landlords to stay on their toes.
A pilot of 10 key papers with differing methodologies was undertaken prior to commencing full data extraction – high levels of agreement were found between the two reviewers.
It is possible that the discrepancies between the different reports are due to the differing methodologies used for the detection of EBV, the histological types of tumours examined, and the ethnic/geographical background of the cases studied.
