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It is a differentiation factor as well as a potent mitogen.
In this study, we propose a new rewarding-punishing coordination mechanism based on trust between supply chain tiers, considered as a differentiation factor between honest and deceptive partners.
We now wished to ascertain whether these synovial cells could be stimulated to transform into chondrocytes, and thus to lay down cartilage tissue, by the timely introduction of a differentiation factor.
Macrophage inflammatory protein-3 alpha (MIP-3α) is a major CC-chemokine family protein, which serves as a differentiation factor for mesenchymal cells, including osteoblasts and dental pulp cells.
Physical distribution service quality is considered as a source of competitive advantage for manufacturers, since it can be viewed as a differentiation factor in the way they are perceived by retailers.
VIP, which is a peptide similar to PACAP, has been reported as a differentiation factor of PC12 cells and other neuronal cells [50] [51].
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Thus, in zebrafish, neurod1 has the capacity to act as a 'cell fate determinant' or a 'cell differentiation' factor.
beta-NGF is a determinant of sympathetic innervation and a neural differentiation factor.
NK cells also enhance production of dendritic cell interleukin-12 (IL-12), which is a key differentiation factor for T helper 1 (Th1) cells, themselves a major source of IFNγ [ 7].
MIP-1 α/CCL3, described as an osteoclast differentiation factor, and RANTES/CCL5, a chemotactic factor for these cells, are found in periodontitis tissues [ 104, 114– 114].
As reported in this issue of Aging by Nakamura et al, age-related resistance of skeletal muscle-derived progenitor cells to SPARC (an autocrine differentiation factor) may explain a shift from myogenesis to adipogenesis (Aging 2012; 4: this issue).
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