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The phrase "a different response to" is correct and usable in written English.
You can use it when discussing varying reactions or answers to a particular situation, question, or stimulus.
Example: "The study aimed to explore a different response to the treatment among diverse patient groups."
Alternatives: "an alternative reaction to" or "a varied reply to".
Exact(59)
Since the treatment assignment was not randomized, there might be differences in the groups that led to a different response to second-line therapies.
Differing goals between outgoing and returning ants may result if a different response to branch asymmetry or a different balance between branch asymmetry and trail pheromone effects.
A different response to the dry Mars scenario appeared in Ray Bradbury's "Martian Chronicles".
They all have a different response to the sports that made them famous.
By contrast, China has chosen a different response to the trilemma.
I suspect, though, that they would have had a different response to the statement "Lying is sometimes necessary to protect oneself".
Donald Fine, chief market analyst at Chase Fleming Asset Management, had a different response to the issue of the age wave and bond yields.
With their routinely understated, meditative albums and their intense, up-tempo live shows, they offer a different response to suburban tensions.
"And research tells us that people have a different response to handing over cash as opposed to handing over a card, whether it be a debit or credit card.
Some of the loudest voices calling for a different response to vulnerability in local communities come from within the police service – and many forces are starting to work differently.
Rychter (2011) offers a different response to Gilmore (2007).
More suggestions(15)
a different solution to
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a distinctive response to
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a varied response to
a dissimilar response to
a distinct response to
a disparate response to
a diverse response to
a different reactions to
a different tack to
a different team to
a different approach to
a different connection to
a different tune to
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com