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Other methods of cartilage injury may produce different results attributable to a difference in proportion of apoptosis to necrosis and/or the timing of apoptotic events.
We were not able to demonstrate a difference in proportion of positive or indeterminate responders among any children <5 years in the SS + group (p>0.3).
However there was a difference in proportion of blindness caused due to cataract.
Therefore, the calculation of the sample size is based on the identification of a difference in proportion of prolonged abstinence after 12 months between these two groups.
We calculated the required sample size to be 130 refugee participants, which is sufficient to detect a difference in proportion affected by a mental health condition by 0.125.
A difference in proportion test was applied to the prevalence of TTN truncations in senior athletes vs. literature controls, as well as the fraction of TTN truncations that map to the Novex-3 exon.
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A series of power analyses were calculated for 2 group comparisons of each risk as a binary outcome (any ongoing risk vs. none) with at least 80% power to detect a difference in proportions of at least 0.125 with the control group proportion in the range 0.10 to 0.90 (2 tailed, α = 0.05), resulting in a target sample size of 526 participants.
The power analysis is based on a z-test for testing for a difference in proportions.
P-values in bold indicate a difference in proportions (risk ratios) significant at the 5% level.
A difference in proportions was considered significant if the chi-square p value was <0.05.
Relative response rates were determined and statistical significance tested for a difference in proportions.
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