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The reference model was statistically superior over the system-specific model in describing the zidovudine data, as demonstrated by a difference in objective function value of 13 points at a 2-point difference in degrees of freedom.
There was a difference in objective RR between both groups (18% vs 0%), but this was not statistically significant (P =.33), possibly because of the small number of objective responses that were noted in this trial.
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Throughout the model building process, an altered model was chosen over a precursor model if a difference in the objective functions (−2 log-likelihood) was >6.63 (P < 0.01, with 1 degree of freedom, assuming an X distribution).
The full model for covariate effects was built using a stepwise inclusion approach based on a p value of 0.05, which corresponds to a difference in NONMEM objective function >3.84 (χ-square distribution, 1 degree of freedom).
However, we did not expect to observe a similar difference in objective parameters.
Moreover, Weyl says, "there is no difference in our experiences to which there does not correspond a difference in the underlying objective situation".
Results of the research indicate that there was a statistically significant difference in objective problem-solving ability scores of CBL group demonstrating higher scores.
A secondary aim was to examine the details of any differences in objective classifications that occur between referring and nuclear medicine physicians.
The goals for these analyses were to assess: 1) any differences in objective versus subjective adherence, and 2) which baseline measures predict adherence in ongoing mindfulness meditation randomized clinical trials being conducted at our lab.
A three-compartment disposition model resulted in a significant improvement in model fit compared with a two-compartment model (difference in objective function value (ΔOFV) of 108) with no additional benefit of an additional peripheral compartment (ΔOFV = 0.57).
There was no significant difference in objective or subjective pain evaluation before the block when comparing patients with normal and impaired cognition (as assessed by the Hindsøe score).
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CEO of Professional Science Editing for Scientists @ prosciediting.com