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Whereas Labandeira-Rey et al. (5 ) provided data that PVL, in combination with staphylococcal protein A, destroys respiratory tissue and bacteria-engulfing immune cells, Voyich et al. (6 ) and Bubeck Wardenburg et al. (7 ) showed that PVL was not essential for the pathogenesis of skin disease, sepsis, or pneumonia in a mouse model.
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