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The phrase "a destabilization in" is correct and usable in written English.
It can be used when discussing changes or disruptions in a system, organization, or environment.
Example: "The recent events have led to a destabilization in the political landscape of the region."
Alternatives: "a disruption in" or "an upheaval in".
Exact(3)
Alternatively, mutation to the smaller aliphatic amino acid side chains led to a destabilization in the active site structure which was accompanied by increases in the partition ratios associated with abortive complex formation.
· History has shown us that when new technologies have been introduced, humanity has experienced a destabilization in the balance of power.
This points to a destabilization in the connection of the Golgi cisternae with the underlying cytoskeleton and suggests, besides a role in retrograde transport, an additional function of the COG complex (or one or more of its subunits) in tethering Golgi membranes to microtubules.
Similar(57)
[Page B1.] The United Nations secretary general, Kofi Annan, warned that "the recent statements directed at Syria should not contribute to a wider destabilization in a region already affected heavily by the war in Iraq".
Background: Mali, one of the poorest countries in the world, already affected by the Sahel nutritional crisis, went through a destabilization process in 2012 when armed rebel groups took control of wide areas of the North and triggered a political crisis in the capital.
A destabilization of Gemin2 in the absence of SMN could explain in part the decrease in cellular Gemin2 observed when SMN levels are experimentally reduced [ 33, 34].
Interestingly, recent work on anesthesia, which selectively erases animal and human consciousness while sparing their non-conscious brain activities, indicates that it might result from a destabilization of MTs in brain neurons.
MMP-9 and gelatinase activity have been shown to cause a destabilization of advanced plaques in mouse models, and in humans MMP-9 is a biomarker for risk of acute coronary events (Gough et al. 2006; Hlatky et al. 2007).
Depletion of USP52 reduced HIF1A mRNA and protein levels and resulted in reduced expression of HIF1A-regulated hypoxic targets due to a 3′-UTR (untranslated region -dependent poly(A)-tail-length-independent destabilization in HIF1A mregion -dependent
"We are seeing a destabilization of the environment in the Arctic.
Incubation at physiological conditions induced ester hydrolysis resulting in a destabilization of the particles making these particles suitable for drug delivery purposes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com