Subthreshold depression, sometimes also called subsyndromal depression or minor depression, refers to a depressive state that does not meet the full diagnostic criteria for major depressive disorder (MDD) [ 1].
Another important factor to be considered is depression since a depressive state could be accompanied by cognitive disturbances in several domains such memory and attention [ 39, 40].
Moreover, various independent studies indicate that patients with diabetes and depression (or in a depressive state) had poorer diabetes self-care and felt that they had less control over their disease (15– 15).
While most patients with MDD have reduced serum BDNF levels, the patients with lower SD showed higher serum BDNF levels than other patients with MDD, suggesting that a depressive state is not linked with depression-related biological changes in these patients.
A diagnosis of depression does not indicate the persistence of a depressive state for every moment of every day, and to conduct analysis using an individual's entire posting history as a single unit of observation is therefore rather specious.
Subjective pain is a common symptom in patients suffering from depression and in turn, chronic pain may trigger a depressive state [44, 45].
The number of CRH expressing neurons, the number of CRH neurons co-expressing AVP, and the amount of CRH-mRNA in the PVN are significantly increased in depressed subjects, independent of whether they died during a depressive state or not (Fig. 3) [ 166].
The affective state was scored using the Geriatric Depression Scale (GDS), in which a high score (>6) denotes a depressive state.
Likewise, the feeling of isolation (significantly associated with depression in multivariate analysis), may be a cause or a consequence of a depressive state.
It resembles a depressive state.
"He's well worth listening to unless he's in a depressive state – then it all becomes a bit pointless".
