Marshall makes a strenuous case for Bishop's social enlightenment, and argues that, while Bishop indeed lived a life of privilege in Brazil, she was nevertheless "an outsider, a dependent whose trust fund met only basic expenses"—a rationale that may make one queasier than anything in the poems.
Was she a dependent sort?
Some respondents indicated that benefits and an ethical rationale were dependent on a specific definition of community, such as within certain geographic boundaries or defined by some common connection.
Considering that the combination effect is schedule-dependent, the rationale would be to administer the gefitinib when chemotherapy is inducing or has induced maximum tumor damage.
On the other hand, suppressing the CXCL-8-dependent pathway provides a valid rationale for melanoma therapy.
Such radiation-induced activation of EGFR-dependent processes may represent a rationale for combined treatment with radiation and EGFR inhibitors.
Insofar as this is true, it provides an additional rationale for excluding dependents from the franchise.
It has also been suggested that focal adhesions are the initiating site of mechanotransduction [ 332], offering an attractive rationale for topography-dependent cell response.
These findings suggest that combinatorial targeting of the hyper-activated oncogenic pathways may represent a therapeutic rationale to switch-off the MYC-dependent epigenetic reprogramming, hampering its tumor initiation capacity.
Additionally, we propose a new rationale that AKT substrates specificity is likely dependent on the ratio between the phosphorylation status of Ser473 and Thr308, rather than Ser473 alone.
The marked differences in cross-taxon congruence of endemic species emerging from the analysis of fine-scale grids [20] and ecoregions [10] might be scale-dependent [20], [24], but there is no a priori rationale for choice of optimal scale.
