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Three hundred patients later, the results were in: Overwhelmingly positive patient feedback and a demonstrated reduction in bed use and emergency room visits, corroborated by independent consultants, quelled the fears of the skeptics.
AP-treated patients showed an improvement in serum creatinine and glutathione S-transferase A1-1 compared to controls, possibly due to a demonstrated reduction in the expression of renal nitric oxide synthase.
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A phase IIa trial of clazosentan (an ETA antagonist) demonstrated reduction in the incidence and severity of angiographic vasospasm [ 154].
On day 11, a chest X-ray demonstrated reduction of pulmonary infiltrates, however the cavitary lesion persisted.
Recently, a report demonstrated a reduction in histone H2A monoubiquitination- a polycomb-induced post-translational modification- in prostate cancer tumor samples [21].
The study demonstrated a reduction in crossing violations and a dramatic reduction in the most dangerous pedestrian behavior.
When maternal mice were administered a daily dose of PEITC, nursing pups demonstrated a reduction in TSB levels (data not shown).
More recently 2 trials of a new form of oral NTHi vaccine have demonstrated a reduction in exacerbations [72, 73].
One of these studies demonstrated a reduction in complication rates [ 97], whilst the other demonstrated a trend towards a reduction in complication rates [ 80].
Each patient demonstrated a reduction of two or more dilutions to at least two anti-HLA antibody specificities.
There are already several programmes in use in Canada, Australia and Sweden, which have demonstrated a reduction in drugs and alcohol use of anything between 20% and 40%.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com