Sentence examples for a deleterious environment from inspiring English sources

However, methylation patterns of genomic imprinting genes tend to be altered by a deleterious environment or manipulation (Anckaert et al. 2010; Khosla et al. 2001).

The intimate dialogue between the (myo)fibroblasts and their microenvironment therefore represents a fascinating domain that must be better understood in order not only to characterize new therapeutic targets and drugs able to prevent or treat pathological developments but also to interfere with skin alterations observed during normal aging or premature aging induced by a deleterious environment.

As a consequence ATM content of adipose tissue is reduced and this contributes to a less deleterious environment.

Despite this obvious environmental contribution to the disease, it is now recognized that T2D pathogenesis is driven by multiple genetic factors interacting with a metabolically deleterious environment [ 21].

Hence, a deleterious fetal environment and more specifically fetal growth restriction induces adaptive changes in the fetal metabolism in order to adjust to a predicted poor postnatal environment.

Our aims are to identify how and where epigenetic modifications fix the effects of early environmental events (overnutrition associated with a deleterious uterine environment) to ensure sustained responses to transient stimuli, leading to the modification of gene expression patterns and phenotypes later in life [41], [68].

In the present article, we propose an alternative way to manage NA in research when investigating the relationship between a deleterious psychosocial environment at work and poor mental health.

In the present article, we propose an alternative method for dealing with negative affectivity (NA) biases in research, while investigating the association between a deleterious psychosocial environment at work and poor mental health.

These cracks also make concrete vulnerable to deleterious environment due to ingress of harmful compounds.

The other toxic gases that lagoons emit, including hydrogen sulfide, methane and carbon dioxide, can also cause deleterious environment and health impacts.

In fact, Esrrb can mediate this effect even in the presence of the complex and supposedly deleterious environment provided by serum and in the absence of LIF.