Sentence examples for a deleterious cycle from inspiring English sources

The pathophysiology of malignant intracranial hypertension is a deleterious cycle of increased intracranial pressure, decreased tissue perfusion, declining intracellular energy production, increasing cellular edema, and subsequent increasing intracranial pressure.

This deficiency puts them at risk,, and disruption of cellular homeostasis leads to SA buildup and NPR1-dependent accumulation of defense related transcripts in a deleterious cycle that is suppressed by mutations in NPR1.

Eventually, in a subset of chronically prion-infected cells, a deleterious cycle leads to initiation of apoptosis that is associated with prominent loss of mitochondria and heightened superoxide generation in the remaining dysfunctional mitochondria, culminating in the death of these cells.

MG can also inhibit the activity of GAPDH (Lee et al. 2005), causing triose phosphate accumulation and thereby increasing MG generation, and so inducing a highly deleterious cycle.

Thus, EMT is a major target to break the deleterious cycle of cancer.

The CD154/CD40 axis also regulates the expression and activation of MMP-1, MMP-9 and MMP-3 on monocytes, which contribute to a deleterious degradative cycle in RA [ 13, 14].

Interruption of this deleterious cycle may improve disease outcome.

Interruption of this deleterious cycle may lead to improved disease outcome.

Interruption of this deleterious cycle with antiviral and/or immunomodulatory therapies may lead to improved disease outcome.

Add to that an exploitative Republican presidential candidate, significant Islamophobia, and a deleterious 24-hour news cycle, and we have a production nearly as distasteful as the film that started it all.

The transgenic plants exhibit a stress response when exposed to air, suggesting that some glyoxylate is diverted away from conversion to glycine in a deleterious short-circuit of the photorespiratory nitrogen cycle.