The phrase "a deleterious combination" is correct and usable in written English.
It can be used to describe a mix of elements that are harmful or damaging in some way.
Example: "The study revealed that a deleterious combination of poor diet and lack of exercise can lead to serious health issues."
Alternatives: "a harmful mix" or "a damaging combination".
A similar effect of the deleterious combination of short sleep duration and insomnia was also observed by Vgontzas et al. [ 7] in a polysomnographic study of insomniacs.
We further demonstrated that otherwise harmless minor bacterial aspiration leads to severe pneumonia and bacteriemia after ischemic stroke suggesting that the deleterious combination of stroke-induced immunodeficiency with stroke-facilitated aspiration dramatically increases the susceptibility to infection [39].
Our present and previous works suggest that degeneration of long peripheral nerves associated with CMT results from the deleterious combination of different pathomechanisms affecting axonal transport.
Our analyses further indicate that selection on swordtail hybrids stems predominantly from deleterious combinations of epistatically interacting alleles.
However, it appears that most of human diseases result from deleterious combinations of polymorphic alleles with small effects on the phenotypes and the diseases elicited by single gene defects are fairly rare.
Interchange haplotypes arise as a result of recombinations between L- and M-opsin genes that create unusual, and potentially deleterious, combinations of exon 3 single-nucleotide polymorphisms (SNPs).
Possible paths for evolution of this sequence can be deduced, starting from any single mutation and following the various lines inward, avoiding deleterious combinations.
Genomic evidence suggests that deleterious combinations of maternal NK cell receptor repertoire and fetal HLA-C and HLA-G antigens can shape a strong inhibitory NK phenotype associated with impaired vascular placental remodeling [ 60].
One possibility is that the multilocus genotypes observed in the evolved lines are the result of selection against deleterious combinations of epistatically interacting alleles segregating among the founder genetic backgrounds.
Two patients harboured a CHEK2 c.1100delC mutation, one of them in combination with a deleterious BRCA2 mutation.
