The phrase "a defining marker of" is correct and usable in written English.
It can be used to indicate a characteristic or feature that is significant in identifying or distinguishing something.
Example: "The ability to adapt to change is a defining marker of successful leaders in today's fast-paced business environment."
Alternatives: "a key indicator of" or "a crucial sign of".
It is well established that over the last decade the seasonally migrating creatures at the top of the economic food chain have turned the pursuit of contemporary art into a defining marker of wealth and social status.
The transcription factor GATA3 is a defining marker of the luminal subtypes.
In this study we have generated a high-resolution binding map of Drosophila HP1, a defining marker of heterochromatin, in the white-mottled PEV model.
Heterochromatin Protein 1 (HP1) is widely accepted as a defining marker of heterochromatin in most eukaryotes, and is also one of the most studied components of heterochromatin [ 14, 15].
CD8A, a defining marker of CD8+ T-cells, was bivalent in all except the CD4+ T-cells, where it was monovalently active, indicating a potential for plasticity among T-cell subsets.
Thus, it is not surprising that Mecp2 has been directly connected to regulation of genes including FoxP3, a defining marker of T regulatory cells [ 68], and interferon (IFN -γ, produced by several IFN -γ cell typroduceduding T lymphocytes and myeloid cells [ 118].
Real-time qPCR data revealed that Hbegf overexpression decreases Alp expression, a defined marker of early osteoblast differentiation.
Forced expression of HB-EGF or treatment with HB-EGF is capable of reducing the expression of alkaline phosphatase (ALP), a defined marker of early osteoblast differentiation.
The overall sample had a BMI of 32.7, with 58% having a BMI greater than or equal to 30 (a commonly defined marker of obesity) and 65% of the participants in the symptomatic knee rOA subgroup being considered obese.
There has been great interest in defining markers of prognosis or pathophysiology in ALI/ARDS.
