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The phrase "a defining explanation of" is correct and usable in written English.
It can be used when you want to describe something that clearly articulates or characterizes a particular concept or idea.
Example: "The article provides a defining explanation of the principles of quantum mechanics."
Alternatives: "a clear description of" or "a comprehensive account of".
Exact(1)
His 1958 collection, A Coney Island of the Mind, has sold over a million copies, with the poem "Constantly Risking Absurdity" a defining explanation of the role of the poet in that era: "Constantly risking absurdity / and death / whenever he performs / above the heads / of his audience / the poet like an acrobat / climbs on rime / to a high wire of his own making".
Similar(59)
A mechanism can be defined as an explanation of an observed phenomenon that explains the processes underlying the phenomenon in terms of events at lower levels of organization.
However, a considerable number of the patients with a non-cardiac/coronary diagnosis do not have a clearly defined explanation for their chest pain.
Completed evaluation was defined as a clinical explanation of the abnormal findings.
Swinburne and his critics leave us with the difficulties of determining what counts as an adequate explanation, of defining simplicity, and of determining prior probabilities.
The impact of prostate cancer therapy on men has been well defined, however, explanation of the consequences of cancer treatment has not been modelled against the wider variables of long-term health-care provision.
The most immediate benefit would be the end of the Texas Board's stranglehold on America's historical literacy (for a funny explanation of how Texas defines our national awareness of historical figures, check out The Daily Show clip below).
Charles Holland designs much more forward-looking developments as part of the architecture practice Fat (it stands for Fashion, Architecture, Taste) and he has a simple explanation of the ersatz traditionalism that defines so many new-build homes.
A straightforward explanation of the use of counterfactuals to define cause can be found in [ 2].
For a more detailed explanation of the variables defined here, see Dill 2006 [ 9], chapters 2.5 and 5.1.
Explanatory models (EM) are defined as an understanding or explanation of episodes of illness and treatment, framed within the context of cultural beliefs and norms of a given society, and employed by all engaged in the clinical process and the interaction between healer and patient that is central to the health care system[ 14].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com