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Firstly, anything that sets a defined threshold for investors' losses has the potential to cause trouble as well as alleviate it.
No male contraception is required if the dose is below a defined threshold for genotoxic concern applicable to small molecules.
They work as guides for human interaction the user can expect, for example, a certain uniformity of traffic speeds but also represent constraints, modifying the field of the possible in respect of individual choices: speed-related behaviors violating a defined threshold, for instance, will be sanctioned ([26], p. 3 sqq).
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This reference antibody concentration of 0.35 µg/mL was defined by the World Health Organization [ 28] to estimate efficacy of PCVs against IPD for infants and is not a defined threshold of protection for other age groups or for this immunocompromised population.
If the difference between observed scores is large, and at least one of the sequence isoforms is a known TFBS or is assigned a score that exceeds a user defined threshold for TFBS presence, the variation is predicted to have a functional impact.
If users wish to eliminate stable mRNA hairpins from their synthetic gene sequences, the back-translation algorithm can be run in "delta G" mode wherein the standard back-translation is carried out together with a user defined threshold for an allowable calculated change in Gibbs free energy (ΔG) for local RNA folding.
Under the hypothesis that Tg-mRNA is expressed at low levels in various human cell lines, and at higher levels in normal or neoplastic thyroid cells, one could consider using a quantitative RT PCR reaction with a clearly defined threshold for detecting Tg-mRNA.
The algorithm used for this study (EXTERIORPTS in SOLO + MIA) uses the extremes of the mean-centered one-norm data as initial guesses based on a user defined threshold for the minimum norm value (a low threshold was used in this study to guarantee that contributions for low Z elements and paints used marginally would be extracted).
Therefore, a precisely defined threshold for instability early warning is necessary.
In situations where the range to be imaged is constituted by isolated targets, with a well defined threshold for deciding upon their existence or not, one can rely on decision-directed estimates in order to improve the imaging of the targets.
This suggests that our approach is giving some reasonable estimate of the energetics of Met4 binding, with a clearly defined threshold for functional binding sites.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com