Exact(3)
These mice develop intimal lesions within 2 weeks at a defined site of the arterial tree, making it an attractive model for drug screening (Lardenoye et al, 2000).
Finally, exposing the pig to its own microbiota by cecal incision induces polymicrobial sepsis with a defined site of infection, often lacking in other experimental models.
Inevitably as a consequence of the strict criteria used to define 'low-risk' in this study, the incidence of positive blood and other cultures was low and the large majority of patients did not have a defined site of infection.
Similar(57)
A defined site (a set of residues) is represented by describing the physiochemical and structural environments surrounded around each residue, referred as FEATURE microenvironment.
We developed an assay to measure the potential of the BRCA1/BARD1 heterodimeric RING complex, which was previously shown to adopt the same structure and have the same biochemical activity as the full-length BRCA1/BARD1 RING complex (Christensen et al., 2007), to ubiquitylate histone H2A at a defined site in the genome of U2OS 2-6-3 cells independently of its association with other proteins.
In this approach, the 3D structure of a wild-type protein is used as a template for modeling protein mutants with amino acid residue substitutions (deletions, insertions) at a defined site, typically at the binding site of the protein.
DNA, containing defined sites of damage, was introduced into mammalian cells to test the role of specific specialized DNA polymerases.
HITS-CLIP has proven to be a reliable means of defining sites of direct functional RNA protein interactions (Licatalosi and Darnell, 2010).
However, as PET images include a greater body area, it may define sites of disease outside the scope of that seen on routine CT scanning.
Therefore, this distance detector system (simultaneous expression of α-AR and β-AR on immune cells) provides a means for the body to define sites of permitted inflammation (low SNS fiber density, low catecholamine concentration) and, on the other hand, prevent uncontrolled spreading of inflammation by preventing bystander activation (high SNS fiber density, high catecholamine concentration).
The modules define sites of interaction with the outer membrane transport genes, TonB, the immunity proteins, and the activity regions.
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Justyna Jupowicz-Kozak
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