Sentence examples for a defined nucleotide from inspiring English sources

RNA virus genomes do not replicate as a defined nucleotide sequence, but as complex and dynamic mutant spectra termed viral quasispecies (reviews in [1], [2]).

However, instead of randomized ssDNA molecules, a fixed sequence with a defined nucleotide sequence containing primer hybridization regions could also be used.

Assuming that any nucleotide substitution at a defined nucleotide site shifts locus S from the advantageous to the disadvantageous state, we defined μ = 2.5 × 10-5 per generation.

Accordingly, we defined a cut off for the description of true heterogeneity at a defined nucleotide position as ≥30%% i.e. if a variant identified in at least 30%% of the Illumina sequencing reads (after filtering and GenomeView analysis), it is likely that the variant is truly present within the genome of a sub-population of bacilli.

Recent bioinformatics studies have revealed that most mammalian genes do not conform to the simple model in which a TATA box directs transcription from a single defined nucleotide position –most genes have multiple promoters, within which there are multiple start sites, and that 72% of human promoters are associated with CpG islands [1] [3].

Alignment of our sequencing results with 62 different T. gondii isolates (5 reference strains, 7 clinical isolates and 51 T. gondii-positive amniotic fluids) revealed 3 nucleotide mutations, one deletion, and one defined nucleotide ambiguity compared to GenBank AF146527.

Raw data is preprocessed before de novo assembly: low-quality nucleotides (we defined nucleotides with a quality score less than 20 as low-quality nucleotides) in the last 20 cycles and ambiguous nucleotides in the first five cycles were trimmed by custom PERL script.

For the detection of the retinoic acid-response element (RARE binding sites, we did an exact forward and reverse search of 18 experimentally defined DR5 RAREs (Mainguy et al. 2003) that consists of five defined nucleotides on each side separated by five arbitrary nucleotides.

Changes in serum Ca2+ or Pi regulate the activity of trans acting interacting proteins in the parathyroid, which alters their binding to a defined 26 nucleotide cis acting instability sequence in the PTH mRNA 3′-untranslated region.

The constructs define nucleotide transition rates and they are applied to choose starting sequences to yield specific nonrandom pools.

Briefly, each unique nucleotide sequence within a defined range of nucleotides was assigned an allele number and translated into amino acids.