The phrase "a defined dose" is correct and usable in written English.
It can be used in contexts related to medicine, pharmacology, or any situation where a specific quantity of a substance is prescribed or measured.
Example: "The doctor recommended a defined dose of the medication to ensure its effectiveness and minimize side effects."
Alternatives: "a specified dose" or "a measured dose."
Thomas DM, Bouchard C, Church T, Slentz C, Kraus WE, Redman LM et al. Why do individuals not lose more weight from an exercise intervention at a defined dose?
Clinical protocols for 177Lu-DOTATATE treatment routinely include mean absorbed dose estimates for the kidneys [1, 2, 5], which usually decide the number of fractions given because of a defined dose limit, even though clinically relevant renal toxicity seldom is observed [6, 7].
14 ICUs (52%) had no specific protocols to guide dosing for patients undergoing RRT. 10 ICUs (37%) dosed these patients with a defined dose per kilogram (ranging from 3 to 7mg/kg) and then used trough levels to guide re-dosing.
Therefore, NHPs infected with a defined dose and strain of Mtb, are ideal for the study of TB granulomas.
A second limitation of our analysis is that the majority of included studies measured FMD acutely, i.e. about 2 hours after ingestion of a defined dose of tea.
Our data suggest that, whereas neither enzyme preparation alone is able to detoxify gluten under simulated gastric conditions, a defined dose ratio of the two enzyme preparations is able to detoxify moderate quantities of dietary gluten.
52 Because of its unique mechanism of action, and a defined dose-limiting toxicity of neutropenia in solid tumors, sapacitabine became an attractive agent to investigate in hematological malignancies.
Mice (n=5/condition) were i.p. injected with a previously defined dose of LPS (50 μg/mouse) or phosphate-buffered saline (PBS).
In a recent study, we found a marked difference between WHO defined doses (WHO DDDs) and doses recommended in hospital guidelines, especially for the penicillins [ 10].
In order to make direct comparisons between different antidepressant classes we converted the total daily dose to a defined daily dose (DDD) using the assumed average daily maintenance dose as given for each antidepressant on the WHO website (www.whocc.no/atc_ddd_index/).
To enable comparison of doses between the antidepressant classes, we converted daily dose to a defined daily dose, by using values assigned by the World Health Organization's Collaborating Centre for Drug Statistics Methodology (www.whocc.no/atc_ddd_index).
