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Where the case turns on the applicability of a state statute or regulation to a particular person or a defined course of conduct, resolution of the unsettled question of state law may eliminate any need for constitutional adjudication.
The study drug, ipilimumab, has a defined course of 4 infusions (not on-going treatment, with corresponding adverse events), and a relatively good safety profile.
In screening tools, each variable should be given a score, thereby quantifying the degree of risk and allowing a direct link to a defined course of action.
To our knowledge we are the first to present analyses of continuous CTC-count status in relation to radiologic response, during a defined course of docetaxel in mCRPC patients.
Studies of sporozoite- and bradyzoite-initiated development in vitro [ 13, 14] support this view, as parasites emerging from infections of human foreskin fibroblasts (HFF) follow a defined course of development evident by nearly synchronous changes in growth and stage-specific gene expression that result in the emergence of bradyzoites 7 10 days later [ 13, 14].
[High-Risk Participant] The usefulness of biomarker values appeared to stem from their apparently 'hard,' tangible nature, and their straightforward connection to a defined course of action: PATIENT: My decision was based upon what we had for biopsies and stuff like that.
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In a rural environment with limited access to caesarean section services, the different values placed on the physical/mental/social dimensions of health have frequently led to a privileging of the medically defined course of care.
Thus, the addition of LAM to PEG-IFNα regimen could not promote the clinical cure in defined course of treatment but brought heavy financial burden to patients.
Additionally, they were cautious about discussing test results if they felt they could not translate them into meaningful and clearly defined course of action for patient treatment.
GEM models of mammary cancer that have defined courses of tumor progression are excellent choices for prevention studies.
It will follow a more defined course, constrained by embankments of capital, funding and risk management.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com