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There are several different platforms that are used to perform this type of analysis and some examples of this are: bead based flow cytometry (e.g., Bio-Plex® and Luminex®), and planar assays containing a defined array of capture microspots deposited in the bottom of the well (e.g., Multi-Array and Aushon Biosystem) [ 12].
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The ribosome is an example for a nanomachine which may be viewed as a three-dimensionally defined array of 51 modular proteins positioned by the rRNA scaffold.
Geometrically regular silicon membrane-based micropore arrays were employed for defined arrays of micrometer-sized interfaces between two immiscible electrolyte solutions (μITIES).
As shown in Figure 1b,c,e, after defining arrays of apertures by electron-beam lithography (EBL) on Cr mask, anisotropic KOH etching to the {111} planes and removing the mask, the inverted pyramidal nanovoid arrays were formed (Figure 1e).
Capture antibodies, specific for each biomarker are bound to the biochip surface defining arrays of test sites.
This precisely defined array possesses the spacing of a 1536 well plate (2.25 mm from the center of one depression to another) maintaining compatibility with liquid handling robots.
In the future, clinical trials with a defined wider array of complementary DNA damage end-points would be necessary.
This assumption is supported by the results of Félidj et al., who reported an enhanced substrate-induced coupling of gold nanoparticles in defined arrays on a gold surface through surface-plasmon traveling waves [ 28].
In a recent paper, Norris et al [ 12] described a novel method to define an array of synthetic peptides that interact specifically with estradiol- or tamoxifen-occupied ER, and regulate their transcriptional activity.
It consists of a single microfluidic channel filled with a liquid scintillator and is designed to define an array of scintillating waveguides each independently coupled to a photodetector.
A single iteration of the simulation of a non-discretized genome operated by defining an array of bases, accumulating reads of a defined length onto that array, and computing the size of the largest contiguous region of occupied bases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com