Schnakenberg et al. reported that egg release from the uterus frequently but sporadically is reduced in females with a deficit of secretory cells, and suggested that secretory cells produce an initial, long-lasting lubricant that coats the uterus.
RepliCel is a regenerative medicine company focused on developing autologous cell therapies (or therapies that involve one individual as both donor and recipient) that address conditions linked to a deficit of healthy cells required for normal healing and function.
For example, Fanconi anemia is associated with congenital malformations, a deficit of blood cell generation in the bone marrow (aplastic anemia), and susceptibility to leukemia.
Furthermore, the animals showed signs of a deficit of interneurons, nerve cells that connect other neurons in neural pathways.
48– 51 These findings suggest that a deficit of vascular endothelial cells can lead to impairment of the functional coordination of the vascular supply in a timely response to the demand created by nervous activity.
API2-MALT1 transgenic mice have a deficit of B220+/CD40+ B-cells in their bone marrow as API2-MALT1-mediated NF-κB activation accelerates their maturation to naïve B-cells [15].
Both genes also affect the enteric nervous system due to a deficit of neural crest-derived cells (Tachibana et al., 2003).
The present study investigated canine great vessels adjacent to the heart, including the aorta, pulmonary artery and vena cava, to identify differences in expression levels of the major contractile and thin filament-binding proteins and thereby fill a deficit of vascular smooth muscle cell research.
Relative to WT neurons, HD140Q/140Q neurons expressed normal levels of Glut3 protein, but displayed less Glut3 on the cell surface, suggesting that there is a deficit of Glut3 trafficking to the cell surface in HD neurons.
In obese individuals, this relationship is curvilinear, with an inflection of blood glucose with a deficit of ∼50% or more beta cells compared with controls.
The low levels of ALDH1A2 in CEPI imply that a deficit of retinoic acid in these cells may be contributing to ovarian cancer by attenuation of the WNT signaling pathway.
