Total joint replacement of a deficient hip is technically difficult with a significant complication rate of excessive shortening, sciatic or femoral nerve palsy, fracture of the femoral shaft, and early postoperative dislocation and aseptic loosening [12, 13, 14].
Replacement of a deficient enzyme in a readily accessible compartment such as blood might prove sufficient to eliminate the toxic compounds in plasma, create a positive diffusion gradient and subsequently clear the freely diffusible toxic compounds from the tissue compartments.
Currently two appropriate treatment options for a deficient or unstable hip are total joint replacement or a pelvic support osteotomy [8, 9, 12].
Fehm MN, Huddleston JI, Burke DW, Geller JA, Malchau H. Repair of a deficient abductor mechanism with Achilles tendon allograft after total hip replacement.
Because of the morbidity related to graft harvest, vertebral body replacement cages have emerged as a viable option for reconstructing a deficient anterior column.
A deficient imagination is a great help as well.
Accusations like this often betray a deficient argument.
a Deficient alveolar ridge.
GBS strains used were NCTC 10/84 (hereafter designated WT), a hemolytic serotype V clinical isolate from neonatal sepsis [23], and its corresponding isogenic β/hc-deficient allelic replacement mutant NCTC:cylEΔcat [21], hereafter designated Δβh/c.
For the generation of Sec7 deficient cells (sec7 - ) we used a gene replacement vector which contained nucleotides 1 to 441 and 1981 to 2469 of the cDNA.
We generated Snap23-deficient mice using a conventional gene replacement targeting method through homologous recombination [15].
