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It was anticipated that the 4435A>G mutation resulted in a deficient nucleotide modification at position 37 of tRNAMet, thereby altering the structure and function of tRNAMet.
A deficient imagination is a great help as well.
Accusations like this often betray a deficient argument.
a Deficient alveolar ridge.
Nrf2-deficient cells exhibit a deficient stress response [ 116].
More recently, Zhou et al. deduced the absence of a ~90 kb S. lividans genomic island in S. coelicolor through analysis of a DNA modification deficient S. lividans derivative ZX7 [ 16].
In this work, C. glutamicum RES167, a restriction and modification-deficient derivative of the wild-type strain ATCC 13032 [ 51] and C. glutamicum RES167Δ rel [ 6] were used.
In addition, the substrates of the deficient enzyme that accumulate upon enzymatic deficiency might undergo a chemical modification such as oxidation, preventing their degradation when the enzymatic activity is recovered [ 54].
This includes RN6390, which is an 8325-4 strain in which three prophage were cured from NCTC 8325 [25], and SA113, which is a mutagenized, restriction-modification deficient derivative of 8325 [10], [26].
A design modification has also helped.
Many practitioners take a behavioral modification approach.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com