Exact(2)
The neurosphere assay represents a method to detect the presence of neural stem cells, however owing to a deficiency of specific and definitive markers to identify them, their quantification and the rate they expand is still indefinite.
Fetal malnutrition can be defined as either overnutrition or undernutrition, or as a deficiency of specific nutrients.
Similar(58)
The development of the autoimmune diabetogenic response results from a thymus dysfunction in programing central self-tolerance to pancreatic insulin-secreting islet β cells, leading to the breakdown of immune homeostasis with an enrichment of islet β-cell reactive effector T cells and a deficiency of β-cell specific natural regulatory T cells (nTregs) in the peripheral T-lymphocyte repertoire.
Although many factors contribute to chemotherapy resistance [ 7], flattening of the dose-response curve at higher drug doses suggests that a deficiency of certain cell-specific factors may play a significant role in decreasing cytotoxicity [ 8].
In contrast, old X chromosomes in Drosophila have become demasculinized, containing a deficiency of genes with male-specific expression [ 27].
Experimentally, there are many attempts to correlate specific components of the emission with the presence or deficiency of specific constituents, particularly oxygen, but it is often difficult to make definitive assignments.
Deficiency of specific subunits leads to the accumulation of various assembly intermediates and to subtly different phenotypes.
We have significantly improved the target-selected mutagenesis gene knockout technology for rats by taking advantage of deficiency of specific MMR function.
● Deficiency of specific ADAMs such as ADAM9, 15 and 17 resulted in decreased growth of heterotopically injected tumour cells in mice models [ 22, 23].
Factors like maternal age at delivery, infections in early life, deficiency of specific nutrients during pregnancy, and/or early childhood have been associated with risk of type 1 diabetes in observational studies [ 4, 5].
Our data are also supported collectively by other spontaneous reports indicating that FGF21 is preferentially induced in the liver upon fasting and starvation, steatosis, obesity, type 2 diabetes and genetic deficiency of specific genes in hepatocytes [ 2, 16- 21, 23- 27, 49].
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