Sentence examples for a defect in the expression of from inspiring English sources

However c-Myb-defective thymocytes had also a defect in the expression of SAP, the signaling molecule required downstream SLAMs [14], [22]-[25], and we did not observe any alterations in SAP expression in dnRas thymocytes.

Osteopetrosis (Csf1op/op) mice have a defect in the expression of macrophage colony stimulating factor (Csf1) [18], [18], which causes a severe deficiency of mature macrophages.

Recent reports have shown that FoxO1 deletion in T cells induces a reduction in the number of peripheral naïve T cells due to a defect in the expression of lymphocyte-trafficking molecules (L-selectin and CCR7) and IL-7Rα [5], [5], indicating a critical role for FoxO1 in homeostasis of naïve T cells.

All RDEB patients studied here carry a defect in the expression of COL7A1 at the protein level, but overexpress the COL7A1-specific RNA about three-fold.

The present study showed that patients with the 5q− syndrome have a defect in the expression of genes involved in ribosome biogenesis and in the control of translation.

For its part, the coi1 mutant also shows insensitivity to JA, thereby causing male sterility, resistance to the inhibition of root development by JA, and a defect in the expression of genes regulated by JA [ 10].

The relative lack of arginine causes a defect in the CD3ζ expression of the tumor-infiltrating T cells.

All seven mutants have a strong defect in the expression of these bradyzoite markers.

In Drosophila, a hypomorphic mutation in spt5 displays defects in the expression of segmental patterning genes [27].

All seven mutants show defects in the expression of the end state bradyzoite genes.

We show that ztf-16 mutants exhibit pronounced remodeling defects, which are explained, at least in part, by defects in the expression of ver-1.