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MPS I is caused by a defect in the gene coding for α-L-iduronidase [ 5].
Cystic fibrosis (CF) is caused by a defect in the CFTR gene, which codes for a protein that carries chloride ions across the cell membrane.
Fixing a defect identified during the coding and unit test phase was five times more expensive than fixing a defect in the design phase.
Such a defect in the translation elongation cycle would be compounded in an exponential way by the length of the protein coding sequence.
"That is a defect in the design".
That's just a defect in the mirror".
An RAPD is a defect in the direct response.
Says Meyer, this is a defect in the system.
The 85 bp deletion and some variations in the 5'flanking region, have not interrupted expression of 1Ay genes, whereas the defects in the coding regions could be responsible to the silence of the 1Ay genes.
The defects in the coding regions (premature stop codons and insertion of large transposon-like elements) would be possibly responsible for the silencing of the 1Ay genes in diploid, tetraploid and hexaploid wheats (Table 2).
The 85 bp deletion and some variations in the 5'flanking region, have not interrupted expression of 1Ay genes, whereas the defects in the coding regions (premature stop codons and insertion of large transposon-like element) would be possibly responsible to the silencing of 1Ay genes.
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