The phrase "a defect in function" is correct and usable in written English.
It can be used when discussing issues related to the performance or operation of a system, device, or process.
Example: "The engineers identified a defect in function that was causing the machine to malfunction."
Alternatives: "a flaw in operation" or "an issue with functionality."
This supports the idea that roX1 ex40 has a defect in function.
Emergence of a new genome with strong selfish drive, but with a defect in function, or introduction of such genome from another lineage will create a natural situation analogous to our experiment.
Immunization of melanoma patients with a broader array of cancer antigens can increase the number of circulating effector CD8 + T cells (eCTLs), but to date this has not correlated with clinical tumor regression, suggesting a defect in function of the eCTLs.
It is also the case that when there is a modest probability of a defect in function and a modest probability of a defect in structure, the fact that the two are in linked by RNFL anatomy increases the value of the SFI compared to when they are not linked.
We are now using this assay to determine thymic function in the autoimmune disease systemic lupus erythematosus to test our hypothesis that a defect in thymic function contributes to lupus pathogenesis.
Mu-Ming Poo of the University of California, Berkeley, agrees, describing the findings as "a very bold link of a molecular defect with a defect in cognitive function".
It is thought that a defect in mucociliary function (through the cystic fibrosis transmembrane conductance regulator (CFTR) gene) results in progressive airway infection.
Hence, the hypothesis of a defect in dFoxo function may help explain the reduced levels of dilp2-3,5 observed in female SdcBG02774 flies.
Although PanK1 was expressed in kidney [10], there was no indication of a defect in kidney function from the serum and urine analysis.
This suggested that a defect in Mpa function and/or proteolysis by the proteasome results in either abrogated pupylation, or possibly increased "de-pupylation" of KasB.
A similar phenomenon was recognized in tumor cells more than 80 years ago [6], and was originally thought to represent a defect in mitochondrial function, perhaps as a result of mutations that occurred during oncogenic transformation.
