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The phrase "a defect in" is correct and usable in written English.
It can be used when discussing flaws or issues within a product, system, or process.
Example: "The engineers discovered a defect in the software that caused it to crash unexpectedly."
Alternatives: "an issue with" or "a flaw in".
Exact(60)
Underlying it is a defect in the way blood vessels respond to the presence of the baby.
"It is a defect in my nature".
That's a defect in some respects.
"That is a defect in the design".
That's just a defect in the mirror".
It's difficult to find a defect in Mourinho.
An RAPD is a defect in the direct response.
Does this reflect a defect in empathy itself?
"There is a defect in a procedural provision that could be repaired".
Women with a defect in BRCA1 have on average a 65% risk of developing breast cancer.
"At this point, it looks like they had a defect in the pipe," he said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com