Southeast Asian ovalocytosis (SAO) is an elliptocytosis, a genetic defect affecting the structural and functional properties of RBCs [Liu et al., 1990].
Iron-deficient anemia can be caused by a lack of dietary iron, blood loss, or a physiologic defect affecting iron bioavailability, uptake, or transfer into the circulation.
Researchers have linked Zika virus to microcephaly — a birth defect affecting the heads and brains of infants born to infected mothers.
The company insisted then, as it does now, that the problem was confined to that plant, but company documents obtained by regulators in 1978 showed that Firestone knew of a design defect affecting tires from other factories as well.
Jacqueline Linder, founder and chief executive of LunchBots in Los Altos, Calif., who handled the 2009 fallout from a product defect affecting 10,000 of her stainless steel food containers: "All this research, testing and data is great, but people really want to know one thing: 'Can I feed this to my kids?
Jacqueline Linder, founder and chief executive of LunchBots in Los Altos, Calif., who handled the fallout from a product defect affecting 10,000 of her stainless-steel food containers in 2009: "People really want to know one thing: 'Can I feed this to my kids?
A conditional Gata3 deficiency starting from the hematopoietic stem cell stage mediated by VavCre results in a developmental defect affecting almost all ILCs (Yagi et al., 2014), consistent with another report showing that a Gata3 germline deletion causes the failure of ILC3 development (Serafini et al., 2014).
These data suggest that ATPalpha CJ mutants have a specific defect affecting intensive or maximal activity.
This is a general defect, affecting the entire system, and should be resolved; however, until this happens, the available information must be used.
