Lee C. Bollinger, president of Columbia University, said in a phone interview that Dr. Moody-Adams would have "an enormous opportunity to shape the future of the undergraduate program," adding that there was a "deep alignment" between her scholarly interests and the "essence of the college's core experience".
Calling: Those who experience their work as a calling are most likely to feel a deep alignment between their vocation and who they are as a person.
Facebook is paying careful attention what Sandberg called a "deep alignment incentive". When the social network helps small businesses grow, Facebook's bottom line grows too.
For example, BamView can be used to inspect the confidence of a deep alignment of short reads, by highlighting base discrepancies.
And that is a key aspect of ethical leadership: seeking deeper alignment between self-interest and common good by integrating a wider range of ethical issues.
Since the observation of a nonconservative rMS at MRE11A position Thr481 in a pair of ataxia-telangiectasia-like disease cases increases the odds that substitutions at this position are in fact pathogenic, it appears that using the evolutionarily deeper alignments is, for the MRN genes, counterproductive.
So how could this deep alignment fail so quickly?
Deep alignment of mammalian species shows little conservation at this residue, but this particular amino acid change is not seen in any other species suggesting it may not be well tolerated.
In contrast, the MRE11A rMS that described from a breast cancer case (p.Thr481Ile), as well as the rMS observed at the same position in a pair of ataxia-telangiectasia-like disease cases (p.Thr481Lys), score as severe C65 substitutions when evaluated with the mammals-only alignment but as likely innocuous C0 substitutions when evaluated with the evolutionarily deep alignment.
A deep end – more alignment with EU standards in Northern Ireland in order to prevent a hard border.
The more he began to focus on building his sense of well-being and self-esteem, the more he began to realize that what he really wanted was to experience himself in alignment with a deeper aspect of who he truly was.
