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The Utah Population Database, a centerpiece of the genetics work, is built upon a deep sampling of some of those families, which have traditionally been huge and sprawling — thus providing a cancer researcher's holy grail of depth across generations.
We here present a deep sampling of the S. dulcamara transcriptome and first assessment of its complexity.
Presently, over 3.8 million sequence reads from 13 diverse libraries are publicly available for Aristolochia fimbriata that provide a deep sampling of expressed gene sequences in this species.
The availability of metagenomic datasets, in particular those that provide a deep sampling of one or more natural populations, is providing an opportunity to test previously proposed evolutionary models.
For example, the reliance on DNA sequence data means that with advances in technology, even a deep sampling of the population (millions of individuals) can be performed rapidly, and observation biases are likely to be less profound than when attempting to glimpse rare and elusive insects or mammals.
The footprints identified by high-throughput sequencing in a ribosome-profiling experiment represent a deep sampling of ribosomes in different states, and thus the ratio of large to small footprints in untreated cells could show, at single-codon resolution, how many ribosomes are in each stage of elongation.
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In all cases, the nipple papilla is cored out or a deep sample of the nipple base is taken during biopsy.
A deep sample of the iliac wing was obtained, ground into a homogenate, placed aseptically on media, and observed for microbial growth; both coagulase-negative Staphylococcus and gram-negative rods grew in 1 culture.
Finally, based on the average likelihood of models evaluated in the fine grid search, all models within 4 log likelihood units of the maximum likelihood model were re-evaluated with a deeper sampling of M = 1,000,000 ARGs, and the average of 10 evaluations taken as the final likelihood value.
A deeper sampling of genes in this species (and in other monocot species) could show that it is, in fact bimodal.
A deeper sampling of species within the Caenorhabditis phylogeny will help elucidate whether a predominantly selfing mode of reproduction in C. elegans and C. briggsae arose recently in their evolutionary history.
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