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This leads to in vitro aging, the accumulation of intracellular oxidative damage, and subsequently a decreased potential for proliferation and differentiation.
In summary, although it has often been assumed that small populations have a decreased potential for adaptation [19], our analyses imply that some rare Acroporid corals may actually have increased adaptive potential as a consequence of introgressive hybridization [20], and therefore may be less vulnerable to extinction than has been assumed.
Otherwise, in CXCR2−/− mice, the orthotopic tumors had a decreased potential to metastasize to the lung [ 38].
Already in passage one cells showed a decreased potential to form multilayers and extended passaging led to the loss of epitheloid cell character.
Mitochondria were dysfunctional and fragmented, with impaired respiration, reduced respiratory chain complex activities, and a decreased potential maintained by reversal of the ATP synthase.
We hypothesize that strains harboring the genomic variant associated with decreased transcription of LYS2 will have a similar reduction of intracellular αAASA concentration and thus a decreased potential for transcriptional activation of Lys14p.
Similar(52)
Moreover, confinement of ions to ordered nanoscale domains offered a platform for creating nearly homogeneous ionic phases with a radically decreased potential barrier to ion conduction.
The lowering of a potent angiogenic cytokine in the luteal phase suggests a possible decreased potential for micrometastasis establishment in that phase.
A temporal shift to the periphery for an actor translates into decreased potential for sustained mobilization.
The design of biofuel cell anodes with substantially decreased potential is a prerequisite for the development of biofuel cells with large open-circuit voltage and power density.
Multifocal ERG showed slightly decreased potentials in a pericentral zone in both eyes.
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